Table 2.
Distribution of serotonin-related gene polymorphisms
| Polymorphism | Genotype | Criminals (n = 194) | Controls (n = 161) | HWE |
Comparison with the control group with Bonferroni correction | |
|---|---|---|---|---|---|---|
| criminals | controls | |||||
| 5HTTLPR in SLC6A4 | L/L | 44 | 26.8 | χ2 = 4.24 | χ2 = 0.47 | χ2 = 10.8 |
| L/S | 39.4 | 51.8 | p = 0.03 | p = 0.99 | p = 0.024 | |
| S/S | 16.6 | 21.4 | ||||
| STin2 in SLC6A4 | 10/10 | 20.7 | 23.5 | χ2 = 4.51 | χ2 = 0.09 | χ2 = 3.8 |
| 12/10 | 41 | 48.1 | p = 0.03 | p = 0.82 | p = 0.148 | |
| 12/12 | 38.3 | 28.3 | ||||
| −1019C>G (rs6295) | C/C | 23.8 | 19.8 | χ2 = 0.8 | χ2 = 0.37 | χ2 = 1.07 |
| C/G | 46.5 | 52.4 | p = 0.36 | p = 0.6 | p = 0.58 | |
| G/G | 29.7 | 27.8 | ||||
| −703G>T (rs4570625) in TPH2 | T/T | 57.2 | 62.5 | χ2 = 0.2 | χ2 = 0.51 | χ2 = 0.97 |
| G/T | 37.6 | 33.3 | p = 0.65 | p = 0.94 | p = 0.614 | |
| G/G | 5.2 | 4.2 | ||||
| rs6318 in HTR2C | G | 83.6 | 94.4 | χ2 = 10 | ||
| C | 16.4 | 5.6 | P = 0.012 | |||
| rs2271537 in TDO2 | A/A | 24.7 | 26.8 | χ2 = 3.38 | χ2 = 1.2 | χ2 = 0.27 |
| A/C | 43.0 | 43.9 | p = 0.06 | p = 0.27 | P = 0.87 | |
| C/C | 32.3 | 29.3 | ||||
Values are presented as numbers unless otherwise stated. HWE, Hardy-Weinberg equilibrium. Bold is only used to highlight those cases with p value <0.05 for the convenience of readers.