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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
The role of botanical bioactive compounds in regulating bone metabolism. They may act directly on the bone cells, or through reducing inflammation and oxidative stress, or indirectly via increasing the level of sex hormones and interacting with sex hormone receptors on bone cells.