Table 1.
The list of validated protein–protein interactions (PPI) among “fished” protein partners 1 of human cytochrome b5 (CYB5A) and ferrochelatase (FECH) as baits by SPR analysis.
| PPI | Kd (Mean Values), M | Reference |
|---|---|---|
| CYB5A/CYP1B1 1 | 7.0 × 10−8 | [12] |
| CYB5A/CYP2C9 | 1.1 × 10−6 | [12] |
| CYB5A/GAPDH | 1.0 × 10−7 | [12] |
| FECH/ADR | 1.3 × 10−5 | [15] |
| FECH/SMAD4 | 1.6 × 10−6 | [15] |
| FECH/CYB5A | 1.5 × 10−6 | [15] |
1 CYP1B1 and CYP2C9—isoenzymes of the cytochrome P450 family, GAPDH—glyceraldehyde-3-phosphate dehydrogenase, ADR—NADPH-adrenodoxin reductase, SMAD4—member 4 of the SMAD family of signal transduction proteins.