Fig. 8. (A) LC-MS chromatograms of M. xanthus DK1622 pcy; (B) pcy ΔpcyJ; (C) pcy ΔpcyK; (D) pcy ΔpcyL and (E) pcy T7A1 pcyO, producing the pyxidicyclines and pyxidicycline precursors. Compounds 3 and 5 are displayed as LC-MS EICs at 341.06 [M + H]⁺ (light green) and 297.075 [M + H]⁺ (orange); the two pyxidicyclines are displayed as LC-MS EICs at 366.10 [M + H]⁺ (1 in orange; 2 in red).