Table 5. Kinetic resolution of (±)-37.
| ||||
| Entry | Conditions a | Conv. (%) | 37 er | 42 er |
| 1 | 3 (10 mol%) | 55 | 77 : 23 | 74 : 26 |
| 2 | 3 (10 mol%) + 14 (1 equiv.) | 56 | 92 : 8 | 85 : 15 |
| 3 | 3 (10 mol%) + PhCO2H (10 mol%) | 53 | 92 : 8 | 89 : 11 |
| 4 | 3 (10 mol%) + 48 (10 mol%) | 56 | 92 : 8 | 83 : 17 |
| 5 | 49 (10 mol%) | 64 | 50 : 50 | 50 : 50 |
aSee ESI for reaction times.