Figure 2.

Scheme of the RAPIDOS approach toward custom-made scaffolds: from standard clinical computed tomography data collection and processing to create specific implant design to development of composite biomaterials for fabrication of implants using additive manufacturing technologies and inclusion of bioactive products. CaP = calcium phosphate particles; HAAC = hydroxypropyltrimethyl ammonium chloride chitosan; Mg = magnesium; PLGA = poly(l-lactide-co-glycolide); PTMC = poly(trimethyl carbonate); RAPIDOS = rapid prototyping of custom-made bone-forming tissue engineering constructs; TCP = β-tricalcium phosphate.