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. 2015 Jun 16;3(3):95–104. doi: 10.1016/j.jot.2015.05.002

Figure 1.

Figure 1

Surgical protocol for the establishment of core-decompression at the distal femur in a SAON rabbit model for implantation of the PLGA/TCP/icaritin substitute biomaterial. (A) The surgical site is exposed by an operating scalpel. (B) A 3.0 mm tunnel is drilled transversely through the distal femora by a trephine. (C and D) The biomaterial is implanted into the bone tunnel. (E–G) Micro-CT three-dimensional image of the bone defect site. (H) X-ray image of the bone defect site. CT = computed tomography; PLGA = poly(lactic-co-glycolic acid); SAON = steroid-associated osteonecrosis; TCP = tricalcium phosphate.