Figure 1.

A schematic image of a custom bioreactor setup. The setup is composed of three components: the pump, the assembly device, and the medium reservoir. Amplification of assembly device shows the internal fluid flow routes. The custom module to assemble the microtissue consists of a cell filter membrane (to avoid cell loss), the outer silicon column, and the nonadhesive wallboard. The thickness between the edge of the column and the inner nonadhesive wallboard is 1–2 mm, which determines the thickness of the vessel wall.