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. 2017 Nov 6;9(3):306–316. doi: 10.1007/s12975-017-0577-8

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© The Author(s) 2017, corrected publication November/2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Stem cells differentiation into blood vessels, neurons, and glia via the upregulation of the survival signal pathway induced by PGZ in OVX/GFP^+BM rats. In the peri-infarct region, double immunohistochemical staining for Musashi-1 (a), GFP (b), and BrdU (c) shows co-localization with NeuN, GFAP, and CD31, respectively. The mRNA level of VEGF (d) was analyzed by quantitative PCR. The protein expression of VEGF, p-Akt, and MAP2 in the peri-infarct region (e) was detected on Western blots and analyzed using LAS 4000 and Image J software. Data are the mean ± SD from eight rats per group. *p < 0.05 vs. VC by ANOVA followed by Scheffe’s test