. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Nov 21;38(1):102–113. doi: 10.1161/ATVBAHA.117.310358

Table 1.

Characteristics of KKAy mice after treatment with AdV-Flot1

Characteristics	KKA^y				KK	p value
Characteristics	PBS	AdV-gfp	AdV-Flot1(Mut)	AdV-Flot1(WT)	PBS	p value
Body weights (g)	42.0 ± 1.0^a	43.6 ± 1.0^a	40.2 ± 0.8^a	38.7 ± 1.2^a	32.8 ± 1.0^b	＜0.002
HbA1c (%)	7.2 ± 0.6^a	7.1 ± 0.5^a	6.8 ± 0.8^a	6.6 ± 0.2^a	5.1 ± 0.1^b	＜0.001
Glucose (mmol/L)	9.6 ± 0.2^a	9.2 ± 0.1^a	8.9 ± 0.5^a	8.7 ± 0.6^a	6.5 ± 0.7^b	＜0.01
Insulin (pmol/L)	168 ± 41^a	172 ± 23^a	208 ± 56^b	198 ± 31^a,b	64 ± 7.3^c	＜0.05
HOMA-IR	10.3 ± 1.7^a	10.1 ± 1.5^a	11.8 ± 2^a	11.0 ± 1.8^a	2.7 ± 0.4^b	＜0.001
Non-esterified Fatty Acid (mEq/L)	0.89 ± 0.07^a	0.83 ± 0.09^a	0.91 ± 0.1^a	0.68 ± 0.05^b	0.71 ± 0.1^b	＜0.01

All data are presented as the mean ±SEM (ANOVA), n=6-8 mice/group. For each characteristic, any two numbers labeled with the same lowercase letter (a, b, c) are statistically indistinguishable. If two numbers do not share a lowercase letter, they are statistically different (P <0.01 [Student-Newman-Keuls post hoc pairwise test]).