Figure 1.

Regions of significant reduction in fractional anisotropy (FA) in patients with schizophrenia (n = 29) compared to healthy controls (n = 20). Red-yellow indicates p_FWE < 0.05. Results are overlaid on the study-specific whole-group mean FA image and the whole-group mean FA skeleton (green). Images are displayed in radiological view (left side of the figure is right side of the brain). Tracts were identified using the Johns Hopkins University Probabilistic Tractography and White Matter Labels Atlases (distributed with FSL). 1: anterior thalamic radiation (left), 2: anterior thalamic radiation (right), 3: corticospinal tract (left), 4: corticospinal tract (right), 5: cingulum (cingulate gyrus) (left), 6: cingulum (cingulate gyrus) (right), 7: cingulum (hippocampus) (right), 8: forceps major, 9: forceps minor, 10: inferior fronto-occipital fasciculus (left), 11: inferior fronto-occipital fasciculus (right), 12: inferior longitudinal fasciculus (left), 13: inferior longitudinal fasciculus (right), 14: superior longitudinal fasciculus (left), 15: superior longitudinal fasciculus (right), 16: uncinate fasciculus (left), 17: uncinate fasciculus (right), 18: body of corpus callosum, 19: genu of corpus callosum, 20: splenium of corpus callosum, 21: superior corona radiata (left), 22: superior corona radiata (right), 23: fornix.