Table 1. Clinical trials with Aurora kinase inihibitors.

No.	Diseases	No.	Diseases
1	21-Hydroxyulase Deficiency	60	Langerhans Cell Histiocytosis
2	Albinism	61	Laron Syndrome
3	Alport Syndrome	62	Leber Hereditary Optic Neuropathy
4	Amyotrophic Lateral Sclerosis	63	Long Chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency
5	Angelman Syndrome	64	Lymphangioleiomyomatosis (LAM)
6	Arginase Deficiency	65	Lysine Urinary Protein Intolerance
7	Asphyxiating Thoracic Dystrophy (Jeune Syndrome)	66	Lysosomal Acid Lipase Deficiency
8	Atypical Hemolytic Uremic Syndrome	67	Maple Syrup Urine Disease
9	Autoimmune Encephalitis	68	Marfan Syndrome
10	Autoimmune Hypophysitis	69	McCune-Albright Syndrome
11	Autoimmune Insulin Receptopathy (Type B insulin resistance)	70	Medium Chain Acyl-CoA Dehydrogenase Deficiency
12	Beta-ketothiolase Deficiency	71	Methylmalonic Academia
13	Biotinidase Deficiency	72	Mitochondrial Encephalomyopathy
14	Cardic Ion Channelopathies	73	Mucopolysaccharidosis
15	Carnitine Deficiency	74	Multi-Focal Motor Neurothy
16	Castleman Disease	75	Multiple Acyl-CoA Dehydrogenase Deficiency
17	Charcot-Marie-Tooth Disease	76	Multiple Sclerosis
18	Citrullinemia	77	Multiple System Atrophy
19	Congenital Adrenal Hypoplasia	78	Myotonic Dystrophy
20	Congenital Hyperinsulinemic Hypoglycemia	79	NAGS Deficiency
21	Congenital Myasthenic Syndrome	80	Neonatal Diabetes Mellitus
22	Congenital Myotonia Syndrome (Non-Dystrophic Myotonia, NDM)	81	Neuromyelitis Optica
23	Congenital Scoliosis	82	Niemann-Pick Disease
24	Coronary Artery Ectasia	83	Non-Syndromic Deafness
25	Diamond-Blackfan Anemia	84	Noonan Syndrome
26	Erdheim -Chester Disease	85	Ornithine Transcarbamylase Deficiency
27	Fabry Disease	86	Osteogenesis Imperfecta (Brittle Bone Disease)
28	Familial Mediterranean Fever	87	Parkinson Disease (Young-onset, Early-onset)
29	Fanconi Anemia	88	Paroxysmal Nocturnal Hemoglobinuia
30	Galactosemia	89	Peutz-Jeghers Syndrome
31	Gaucher's Disease	90	Phenylketonuria
32	General Myathenic Gravis	91	POEMS Syndrome
33	Gitelman Syndrome	92	Porphyria
34	Glutaric Acidemia Type I	93	Prader-Willi Syndrome
35	Glycogen Storage Disease (Type I, II)	94	Primary Combined Immune Deficiency
36	Hemophilia	95	Primary Hereditary Dystonia
37	Hepatolenticular Degeneration (Wilson Disease)	96	Primary Light Chain Amyloidosis
38	Hereditary Angioedema (HAE)	97	Progressive Familial Intrahepatic Cholestasis
39	Hereditary Epidermolysis Bullosa	98	Progressive Muscular Dystrophies
40	Hereditary Fructose Intolerance	99	Propionic Acidemia
41	Hereditary Hypomagnesemia	100	Pulmonary Alveolar Proteinosis
42	Hereditary Multi-infarct Dementia (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalqpathy, CADASIL)	101	Pulmonary Cystic Fibrosis
		102	Retinitis Pigmentosa
		103	Retinoblastoma
43	Hereditary Spastic Paraplegia	104	Severe Congenital Neutropenia
44	Holocarboxylase Synthetase Deficiency	105	Severe Myoclonic Epilepsy In Infaricy (Dravet Syndrome)
45	Homocysteinemia	106	Sickle Cell Disease
46	Homozygous Hypercholesterolemia	107	Silver-Russell Syndrome
47	Huntington Disease	108	Sitosterolemia
48	Hyperornithinaemia-Hyperammonaemia-Hhomocit rullinuria Syndrome	109	Spinal and Bulbar Muscular Atrophy (Kennedy Disease)
		110	Spinal Muscular Atrophy
49	Hyperphenylalaninemia	111	Spinocerebellar Ataxia
50	Hypophosphatasia	112	Systemic Sclerosis
51	Hypophosphatemia Rickets	113	Tetrahydrobiopterin Deficiency
52	Idiopathic Cardiomyopathy	114	Tuberous Sclerosis Complex
53	Idiopathic Hypogonadotropic Hypogonadism	115	Tyrosinemia
54	Idiopathic Pulmonary Arterial Hypertension	116	Very Long Chain Acyl-CoA Dehydrogenase Deficiency
55	Idiopathic Pulmonary Fibrosis	117	Williams Syndrome
56	IgG4 related Disease	118	Wiskott-Aldrich Syndrome
57	Inborn Errors of Bile Acid Synthesis	119	X-linked Agammaglobulinemia
58	Isovaleric Acidemia	120	X-linked Ldrenoleuko Dystrophy
59	Kallmann Syndrome	121	X-linked Lymphoproliferative Disease

*From the Notice on the First National List of Rare Diseases in China jointly issued by five bodies, including the National Health Commission. (1).