Table 1. The hot mutation sites of Chinese patients.
Number of Patients | Disease type | Pathogenic gene | Frequent mutation site | Ref. |
---|---|---|---|---|
16 | cblC | MMACHC | c.609G>A /c.658_660delAAG | (12) |
43 | isolated MMA | MUT | c.729_730insTT | (10) |
79 | cblC | MMACHC | c.609G>A, c.658_660delAAG, c.482G>A, c.394C>T, c.80A>G | (11) |