Table 1.

Summary of Model Projections After Following the Recommended Guidelines Set by the World Health Organization (WHO) and Suggestions for Programmatic Adaptations in Cases Where the WHO Goals Are Not Achieved for Schistosoma mansoni

Baseline Prevalence in SAC	Morbidity Goal Reached?	Elimination as a Public Health Problem Goal Reached?	Programmatic Adaptation
Low (<10%)	Yes; within 6 years	Yes; within 6 years	Not required
Moderate (10%–50%)	Yes; within 6 years	Varies depending on scenario	Increase PCT to once a year OR increase coverage to 85% for SAC and include adult treatment at 40% coverage
High (≥50%)	Varies depending on scenario	Varies depending on scenario	Increase PCT from once a year to twice a year (where year 6 prevalence has fallen between 10% and 50%) or from twice a year to 3 times a year (where year 6 prevalence has fallen ≥50%) OR increase coverage to 85% for SAC and include adult treatment at 40% coveragea

The World Health Organization goals are shown in Figure 1.

Abbreviations: PCT, preventive chemotherapy; SAC, school-aged children.

^aWe recommend increasing coverage and expanding to include adult coverage rather than increasing treatment frequency to 2 or 3 times a year due to logistical issues, such as adherence to treatment.