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. 2017 Dec 13;33(6):923–934. doi: 10.1093/ndt/gfx304

FIGURE 8.

FIGURE 8

CD41 and collagen content in GPx3−/− myocardium after surgically induced CKD. (A) four weeks after CKD, CD41+ thrombi per total cell number per hpf in GPx3−/− + sham (0.03 ± 0.01) (n = 9) versus GPx3−/− + CKD (0.17 ± 0.05) (n = 9) mice (*P < 0.001) and WT + CKD (0.03 ± 0.01) (n = 9) versus GPx3−/− + CKD mice (**P < 0.001). (B) Collagen content per total pixel area after 8 weeks: WT + sham (0.19 ± 0.04) (n = 10) mice versus WT + CKD (0.38 ± 0.07) (n = 10) mice (*P < 0.001), GPx3−/− + sham (0.21 ± 0.05) (n = 10) versus GPx3−/− + CKD (0.51 ± 0.08) (n = 10) mice (**P < 0.001) and WT + CKD versus GPx3−/− + CKD mice (†P = 0.002).