(A).

Variable	Multivariate p-value	HR	95% IC
bR > 16 weeks	0.003	0.012	0.00001–0.284
Presence of lung metastases	0.273	2.164	0.536–9.517
Presence of non-lung visceral metastases	0.431	0.462	0.066–3.440
Baseline LDH level	0.708	1.001	0.996–1.007
Baseline ctDNA level	0.164	0.999	0.998–1.000