(B).

Variable	Multivariate p-value	HR	95% IC
bR > 16 weeks	0.014	0.067	0.0005–0.631
Presence of lung metastases	0.236	2.118	0.621–8.662
Presence of non-lung visceral metastases	0.295	2.283	0.494–12.460
Baseline LDH level	0.297	0.998	0.993–1.002
Baseline ctDNA level	0.039	1.0001	1.0000–1.0003