Table 2. Correlation between BDNF expression level and the clinicopathological characteristics of the 44 OSCC patients.
| Variables | BDNF | P value | ||
|---|---|---|---|---|
| Low | High | |||
| Gender | M | 13 | 10 | 0.72 |
| F | 13 | 8 | ||
| T classification | T1 | 14 | 11 | 0.63 |
| T2 | 12 | 7 | ||
| Stage | I | 14 | 11 | 0.63 |
| II, III, IV | 12 | 7 | ||
| Nodal metastasis | – | 25 | 15 | 0.18 |
| + | 1 | 3 | ||
| Lymphovascular invasion | – | 25 | 14 | 0.081 |
| + | 1 | 4 | ||
| Vascular invasion | – | 23 | 16 | 0.67 |
| + | 3 | 2 | ||
| Neuroinvasion | – | 26 | 15 | 0.062 |
| + | 0 | 3 | ||
| Muscle invasion | – | 14 | 4 | 0.036* |
| + | 12 | 14 | ||
| Differentiation | Well | 21 | 4 | <0.001*** |
| Mod/Por | 5 | 14 | ||
| TRKB expression | Low | 17 | 2 | <0.001*** |
| High | 9 | 16 | ||
Statistical analyses were performed using Pearson's χ2 test or Fisher's exact test. *P < 0.05 and ***P < 0.001. M, male; F, female; Well, well differentiated OSCC; Mod/Por, moderately or poorly differentiated OSCC.