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. 2018 May 18;9(38):25148–25165. doi: 10.18632/oncotarget.25358

Figure 4. Gene Set Enrichment Analysis of cisplatin ALDHhighCD44high vs. control ALDHhighCD44high cells.

Figure 4

Gene set enrichment analysis using “Hallmark” gene sets based on comparison between cisplatin ALDHhighCD44high and control ALDHhighCD44high cells. (A–C) Gene sets enriched in cisplatin ALDHhighCD44high cells with FDR < 0.25 and p-value < 0.05. (A) Interferon Alpha Response, (B) TNFα Signaling Via NF-κB, (C) IL6-JAK-STAT3 Signaling. (D–E) Gene sets enriched in control ALDHhighCD44high cells with FDR < 0.25 and p-value < 0.05. (D) Hypoxia, (E) Notch Signaling. NES–Normalized Enrichment Score.