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. 2018 May 18;9(38):25181–25192. doi: 10.18632/oncotarget.25388

Table 1. Comparison of L858R detection on different plasma DNA isolation systems.

PlasmaDNA
200-M 200-A 1000-A
L858R
Positive
L858R
Negative
L858R
Positive
L858R
Negative
L858R
Positive
L858R
Negative
Tissue L858R
Positive
(n = 41)
15 26 24 17 31 9
L858R
Negative
(n = 30)
2 28 0 30 1 29
Total (n = 71) 17 51 24 47 32 38
Sensitivity 36.6% 58.8% 77.5% **P < 0.01
Specificity 93.3% 100% 96.7% P = 0.36
Concordance 60.6% 76.1% 85.7% **P < 0.01