Table 1. Comparison of L858R detection on different plasma DNA isolation systems.
PlasmaDNA | ||||||||
---|---|---|---|---|---|---|---|---|
200-M | 200-A | 1000-A | ||||||
L858R Positive |
L858R Negative |
L858R Positive |
L858R Negative |
L858R Positive |
L858R Negative |
|||
Tissue | L858R Positive (n = 41) |
15 | 26 | 24 | 17 | 31 | 9 | |
L858R Negative (n = 30) |
2 | 28 | 0 | 30 | 1 | 29 | ||
Total (n = 71) | 17 | 51 | 24 | 47 | 32 | 38 | ||
Sensitivity | 36.6% | 58.8% | 77.5% | **P < 0.01 | ||||
Specificity | 93.3% | 100% | 96.7% | P = 0.36 | ||||
Concordance | 60.6% | 76.1% | 85.7% | **P < 0.01 |