Table 3. Meta-analytic estimates of breast cancer penetrance (× 100) in Asian women who carry BRCA1 or BRCA2 mutations.

Study	Korea	Beijing	Hong Kong	Meta-analytic Estimates
Age Interval	Penetrance (%) (95% CI)	Penetrance (%) (95% CI)	Penetrance (%) (95% CI)	Penetrance (%) (95% CI)
BRCA1
20-40 years	10 (2-45)	2.2 (0-4.4)	10.0 (4.7-15.7)	5.2 (1.3-18.2)
20-50 years	27 (5-84)	9.9 (3.3-17.2)	16.3 (8.6-25.0)	13.6 (8.9-20.3)
20-60 years	41 (9-95)	29.3 (17.6-47.1)	30.5 (18.0-46.6)	30.9 (21.5-42.2)
20-70 years	49 (11-98)	37.9 (24.1-54.4)	53.7 (34.5-71.6)	44.8 (33.0-57.2)
BRCA2
20-40 years	6 (3-15)	1.2 (0-3.1)	6.7 (3.2-11.0)	4.5 (1.8-10.7)
20-50 years	18 (8-39)	10.7 (9.6-16.9)	21.1 (12.3-31.1)	15.8 (10.1-24.1)
20-60 years	28 (13-56)	27.2 (19.0-38.5)	31.4 (21.6-42.6)	29.6 (23.1-36.9)
20-70 years	35 (16-65)	36.5 (26.7-51.8)	48.3 (31.8-68.5)	40.7 (31.3-50.9)