Table 5. Number of total and genotyped first degree relatives from the 66 BRCA1 families, 84 BRCA2 families, and 1485 non-carrier families.
BRCA1 | BRCA2 | Non-carrier | ||||
---|---|---|---|---|---|---|
Total No. (%) |
Per Family Median No. (IQR) |
Total No. (%) |
Per Family Median No. (IQR) |
Total No. (%) |
Per Family Median No. (IQR) |
|
First Degree Relatives | 230 (77.7) | 3 (2-4) | 309 (78.6) | 3 (2-4) | 5410 (78.4) | 3 (2-5) |
Mother | 66 (28.7) | 1 (1-1) | 84 (27.2) | 1 (1-1) | 1485 (27.4) | 1 (1-1) |
Daughter | 37 (16.1) | 0 (0-1) | 48 (15.5) | 0 (0-1) | 967 (17.9) | 0 (0-1) |
Sister | 127 (55.2) | 1 (1-3) | 177 (57.3) | 2 (1-3) | 2958 (54.7) | 2 (1-3) |
Carriers | 37 (16.1) | 1 (1-2) | 45 (14.6) | 1 (1-2) | 1 (<0.1) | 0 (0-0) |
Non-carriers | 38 (16.5) | 0 (0-1) | 38 (12.3) | 0 (0-1) | 19 (0.4) | 1 (1-1) |
Un-genotyped | 155 (67.4) | 2 (1-3) | 226 (73.1) | 2 (1-3) | 5390 (99.6) | 3 (2-5) |
IQR: Interquartile range.