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Histone over-expression analysis. A: Effect of histone over-expression in hif1Δ, hat1Δ, hat2Δ and lsm1Δ mutant strains. Note: Growth on galactose turns GAL1 promoter ON resulting in histone over-expression (O/E) B: Tetrad analysis of yeast strains. Yeast haploid strains lsm1Δ and hif1Δ, hat2Δ, and hat1Δ were crossed. Representative tetrads that were dissected for each cross are shown. Double mutants are shown as circles.
