Table 1.

Selected 2012 WHO Early Warning Indicator definitions and targets

Early Warning Indicator	Definition	Definition (Numerator/Denominator)	Targets
On time pill pick up	Percentage of patients (adults or paediatric) that pick-up ART no more than two days late at the first pick-up after the baseline	Numerator: Number of patients picking up their ART “on time”* at the first drug pick-up after baseline pick-up date Denominator: number of patients who picked up ARV drugs on or after the designated EWI start date	Red: < 80% Amber: 80%–90% Green: > 90% Pediatric targets same as adults
Retention in care	Percentage of adults and children known to be alive and on treatment 12 months after ART initiation.	Numerator: Number of adults and children who are still alive and on ART 12 months after initiating treatment Denominator: Total number of adults and children who initiated ART who were expected to achieve 12-month outcomes within the reporting period, including those who have died since starting therapy, those who have stopped therapy, and those recorded as lost to follow-up at month 12	Red: < 75% Amber: 75%–85% Green: > 85% Pediatric targets same as adults
Pharmacy stock-outs	Percentage of months in a designated year in which there were no ARV drug stock-outs	Numerator: Number of months in the designated year in which there were no stock-out days of any ARV drug routinely used at the site Denominator: 12 months	Green: 100% Red: < 100% Pediatric targets same as adults
Dispensing practices	Percentage of adults and children prescribed of picking up mono or dual ARV therapy	Numerator: Number of patients who pick-up from the pharmacy, a regimen consisting of one or two ARVs Denominator: number of patients picking up ARVs on or after the designated EWI sample start date.	Green: 0% Red: > 0% Pediatric targets same as adults

^*“on-time” as it relates to pill pick-up is defined as a patient picking up their ART within 2 days of their previous prescription running out if taken according to schedule.