Figure 1: Serum Cortisol Levels after Administration of Three Daily Doses of Hydrocortisone or a Single Dual-release Hydrocortisone Preparation Compared with Physiological Average Concentration.

Serum cortisol levels after administration of three daily doses of hydrocortisone (dashed line) or a single dual-release hydrocortisone preparation (Plenadren^® 20 mg) (dotted line) compared with physiological average concentration (continuous line). Permission obtained from Falorni et al., 2013.⁶