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. 2018 Apr 17;12(6):788–798. doi: 10.1002/1878-0261.12172

Figure 4.

Figure 4

ATF3 and ATF4 contribute to Noxa induction by cisplatin treatment. (A) HN8 and HN12 cells were treated with cisplatin (50 μm for HN8 or 25 μm for HN12) for the indicated times. Equal amounts of the total extracts were used for immunoblot analysis with the indicated antibodies. (B, C) HN8 (B) or HN12 (C) cells were infected with lentiviruses encoding shRNA for nontargeting control, ATF3, or ATF4. Cells were treated with cisplatin for 16 h and equal amounts of the total extracts were used for immunoblot analysis with the indicated antibodies.