Table 2.
RNA-seq profiling of long noncoding RNAs (lncRNAs) following immune activation
| Stimulant | Species | Cell/tissue type | lncRNAs (up-regulated) | lncRNAs (down-regulated) | References |
|---|---|---|---|---|---|
| TNF-α | Mouse | MEFs | 166 | Rapicavoli et al. 2013 | |
| Pam3CSK4 | Mouse | BMDMs | 62 | 62 | Carpenter et al. 2013 |
| Pam3CSK4 | Human | THP1s (monocytic cell line) | 156 | Li et al. 2014 | |
| IFN-α | Human | Hepatocytes | ∼120 | ∼100, exact number not reported | Kambara et al. 2014 |
| IAV | Human | Alveolar cells | 494 | 413 | Ouyang et al. 2014 |
| EV71 | Human | Rhabdomyosarcoma cells | 2990 | 1876 | Yin et al. 2013 |
| SARS-CoV | Mouse | Lung | 1500 | Peng et al. 2010 |
TNF-α, Tumor necrosis factor α; MEFs, murine embryo fibroblasts; BMDMs, bone-marrow-derived macrophages; IFN-α, interferon α; IAV, influenza A virus; SARS-CoV, severe acute respiratory syndrome coronavirus.