Skip to main content
. 2018 Apr 12;37(11):e97780. doi: 10.15252/embj.201797780

Figure 3. YAP overcomes Ras‐induced inhibition of dNTP metabolism in primary human fibroblasts.

Figure 3

  1. qPCR for dNTP metabolism genes in WI38 cells infected with Ras or Ras together with YAP 5SA. Control cells (−) were infected with an empty virus. Here and throughout Figs 4 and 5, cells were harvested 6 days after starting selection of infected cells with puromycin. n = 6.
  2. Western blot analysis of WI38 cell extracts infected as in (A). GAPDH is the loading control. Two independent experiments.
  3. Steady‐state size of dNTP pools in WI38 cells infected as indicated in (A). n = 4.
Data information: Data are mean and SD with *P < 0.05 (two‐tailed Student's t‐test).