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. 2018 Apr 12;37(11):e97780. doi: 10.15252/embj.201797780

Figure EV3. YAP/TAZ regulate nucleotide metabolism genes in human primary fibroblasts.

Figure EV3

  • A
    qPCR for endogenous nucleotide metabolism genes in WI38 cells that were infected with control (−) or YAP 5SA‐encoding retroviruses (4 days), or transfected with the indicated siRNAs (48 h): control (siCo.), YAP/TAZ (siYT). Control cells were arbitrarily set to 1. n = 4.
  • B
    qPCR for YAP and TAZ mRNA levels in WI38 cells. n = 4.
  • C, D
    WI38 cells were transfected with control siRNA (siCo.) or YAP/TAZ siRNA (siYT) and, 8 h later, were infected with the indicated vectors. Cells were collected at 2 days (see Materials and Methods) and assayed by qPCR analysis on Myc (B) or nucleotide metabolism genes (C). n = 4.
Data information: Data are mean and SD with *P < 0.05 (two‐tailed Student's t‐test).