Table 3.

Crypt score = product of percentage of crypt change and crypt distortion, graded out of a maximum score of 8.

Crypt Grade		Quantification of the Percentage of Crypt Change		Crypt Distortion—Graded Based on the Extent of Involvement
Grade 0:	Intact crypt	1	1–25%	0	No crypt distortion
Grade 1:	Shortening and loss of basal 1/3 of crypts	2	26–50%	1	1–25%
Grade 2:	Loss of basal 2/3 of crypts	3	51–75%	2	26–50%
Grade 3:	Loss of entire crypt with intact surface epithelium	4	76–100%	3	51–75%
Grade 4:	Loss of both entire crypt and surface epithelium (erosion)			4	76–100%