Table 1.
The antibacterial activities of chromatography Fraction 5 (eluting with 100% MeOH) from the extracts of Pseudomonas sp. grown in four different media were tested in a growth inhibition assay. Cytotoxic activities of the fractions were evaluated with a cell viability assay. Test concentration for both assays was 50 µg/mL.
| Growth Inhibition Assay | Viability Assay | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Media | E. coli N | S.aur P | P.aer N | E.F P | S.aga P | A2058 | MCF7 | HT29 | MRC5 * |
| VR_1 | − | − | − | − | + | − | − | − | − |
| VR_2 | − | − | − | + | + | − | − | − | − |
| M19 | − | + | − | + | + | + | + | + | + |
| SGC | − | − | − | − | − | − | − | − | − |
Antibacterial assay: +, OD600 nm < 0.05 and active; −, OD600 nm > 0.05 and inactive. P Gram-positive; N Gram-negative. S.aur, S. aureus; P.aer, P. aeruginosa; E.F, E. faecalis; S.aga, S. agalactiae. Viability assay: +, >50% cell death; −, <50% cell death. * Non-malignant cell line.