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. 2018 May 18;16(5):171. doi: 10.3390/md16050171

Table 5.

EC50 values of the effect of whelk GAGs fragments produced by heparinases I, II, and III and chondroitinase ABC on TNBC cell lines.

- Cell Line EC50 µg/mL
Crude Whelk GAGs
EC50 µg/mL
Whelk GAGs + Heparinase I
EC50 µg/mL
Whelk GAGs + Heparinase II
EC50 µg/mL
Whelk GAGs + Heparinase III
EC50 µg/mL
Whelk GAGs + Heparinase I, II, and III
EC50 µg/mL
Whelk GAGs + Chondroitinase ABC
1 MDA-MB-468 2.80 ± 0.02 2.60 ± 0.01 42.30 ± 0.02 37.90 ± 0.03 33.20 ± 0.01 3.00 ± 0.01
2 MDA-MB-231 3.50 ± 0.01 14.00 ± 0.01 24.90 ± 0.03 26.00 ± 0.03 27.60 ± 0.02 4.60 ± 0.01