Skip to main content
. 2018 May 7;128(6):2519–2534. doi: 10.1172/JCI97053

Figure 9. Lymphomas from individual aged vPK mice are monoclonal or polyclonal.

Figure 9

D–JH segments of IgH in genomic DNA were PCR amplified, electrophoresed, and stained with ethidium bromide. D–JH segments of IgH in normal WT spleens (WT Sp) and vPK lymphomas. Node, mouse 3; liver, mice 4, 7, and 13; spleen, mice 6, 8–12, and 14. Asterisks indicate the preferential amplification of 1 D–JH segment. A total of 20 lymphoma tissues each from a different aged vPK mouse were evaluated. Polyclonal, n = 12; monoclonal, n = 8.