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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Cell Rep. 2018 May 8;23(6):1817–1830. doi: 10.1016/j.celrep.2018.04.026

Figure 7. Model for Early Steps of Capsid Assembly Across the AAP Phenotypes.

Figure 7

Whether a serotype is AAP-dependent, AAP-independent, or AAPC-independent, nucleating capsid assembly is likely dependent on both the stability and oligomerization of VP proteins. Our findings demonstrate that AAP is active in both functions. Whether these functions are discrete is unclear and indicated by question marks in the model.