Table 1. Summary of statistical tests used to determine genome-wide spatial correlations between extracellular receptor-like proteins (RLPs) and secreted peptides (SPs) versus intracellular nucleotide-binding leucine-rich repeat receptors (NLRs).

	Query	Reference	Relative Kolmogorov-Smirnov P-valuea	Relative ECDF area correlationb	Relative ECDF deviation area P-value			Jaccard measure P–value			Projection test P–value
						Closec	Far		Overlapd	N		Overlap	N
eLRR vs. NLR genese	256	366	3.2E-06	0.152	<0.01	✓	✓	0.43		✓	0.44	✓
NLR vs. eLRR genese	366	256	0.862	-2.2E-04	0.72		✓	0.40		✓	0.34	✓
RLP vs. NLR genes	152	366	1.2E-04	0.141	0.01	✓		0.44	✓		0.29	✓
NLR vs. RLP genes	366	152	0.007	0.046	0.07	✓		0.45	✓		0.24	✓
SP vs. NLR genes	104	366	0.009	0.167	<0.01	✓		0.25	✓		0.21	✓
NLR vs. SP genes	366	104	3.8E-04	0.064	0.02	✓		0.38	✓		0.14	✓
SP vs. RLP genes	104	152	0.010	0.129	0.03	✓		0.12	✓		0.07	✓
RLP vs. SP genes	152	104	8.2E-05	0.241	<0.01	✓		0.05	✓		0.06	✓
LRR vs. ribosomal genese	622	1134	0.002	-0.054	<0.01		✓	<0.01		✓	0.21		✓
Ribosomal vs. LRR genese	1134	622	0.289	0.021	0.21	✓		<0.01		✓	0.02		✓
LRR vs. all other genese	622	80305	0.000	-0.261	<0.01		✓	<0.01		✓	8.9E-78		✓
All other genes vs. LRRe	80305	622	2.4E-04	0.009	<0.01	✓		<0.01		✓	#######		✓

^a P values are shown for all tests in both directions, using one dataset as a query and the other one as a reference.

^b ECDF: Empirical Distribution Cumulative Function

^c For the relative distance test, positive and negative relative ECDF area correlation values are labeled as close and far, respectively.

^d The outcome of Jaccard and projection tests is defined as overlapping or non-overlapping (N).

^e The combination of RLP and SP genes are referred to as eLRR genes. Control comparisons include those of all predicted leucine-rich repeat (LRR) genes, consisting of RLP, NLR and SP genes, to ribosomal genes or those to all other coding genes of the Brassica napus genome.