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. 2018 Jun 1;13(6):e0198387. doi: 10.1371/journal.pone.0198387

Table 3. Effects of the pre-end-stage renal disease pay-for-performance program on the 3-year mortality after dialysis.

Events (Incidence per 1,000 patient year) Adjusted hazard ratio (95%CI) PS-matched hazard ratio (95%CI)
Model 1 Model 2 Model 3 Model 4
All cause
 Non-P4P 8485 (171.6) 1.00 [Reference] 1.00 [Reference] 1.00 [Reference] 1.00 [Reference]
 P4P 2216 (125.1) 0.71 (0.67–0.74) 0.71 (0.68–0.74) 0.78 (0.75–0.82) 0.77 (0.73–0.82)
Cause of death
Cardiovascular disease
 Non-P4P 598 (12.1) 1.00 [Reference] 1.00 [Reference] 1.00 [Reference] 1.00 [Reference]
 P4P 117 (10.0) 0.86 (0.73–1.02) 0.85 (0.72–1.00) 0.86 (0.73–1.03) 0.79 (0.64–0.96)
Infectious disease
 Non-P4P 2331 (47.1) 1.00 [Reference] 1.00 [Reference] 1.00 [Reference] 1.00 [Reference]
 P4P 609 (34.4) 0.74 (0.68–0.81) 0.75 (0.69–0.82) 0.85 (0.77–0.93) 0.81 (0.72–0.90)
Cancer
 Non-P4P 372 (7.5) 1.00 [Reference] 1.00 [Reference] 1.00 [Reference] 1.00 [Reference]
 P4P 110 (6.2) 0.88 (0.71–1.09) 0.88 (0.71–1.10) 0.90 (0.72–1.13) 0.86 (0.67–1.11)
Out-off-hospital cardiac arrest
 Non-P4P 770 (15.6) 1.00 [Reference] 1.00 [Reference] 1.00 [Reference] 1.00 [Reference]
 P4P 178 (10.0) 0.66 (0.56–0.78) 0.66 (0.56–0.78) 0.68 (0.57–0.80) 0.65 (0.54–0.79)

Abbreviation: P4P, pay for performance; CI, confidence interval; PS, propensity score.

Subdistribution hazard model was used to estimate cause-specific mortality after consideration of competing risk of other causes.

Model 1: adjusted patient characteristic (age, sex, socioeconomic status, urbanization, and modality).

Model 2: adjusted factors listed in model 1+major coexisting disease (hypertension, diabetes, cardiac disorder, ischemic stroke, gout, and peripheral vascular diseases), and Charlson score.

Model 3: adjusted factors listed in model 2+ confounding drugs (diabetic drugs, anti-hypertensive drugs, analgesic drugs, anti-lipid drugs, erythropoietins).

Model 4: analysis only in patients with propensity score matching.