Table 2. Subjects’ demographic, anthropometric, biochemical and clinical characteristics before bariatric surgerya.
| Cluster 1 (n = 24) | Cluster 2 (n = 15) | P | |
|---|---|---|---|
| Type of surgery, RYGB (nSG) | 13 (11) | 13 (2) | 0.05* |
| Gender, nF(nM) for RYGB, SG | 10 (3), 6 (5) | 10 (3), 1(1) | 0.73* |
| Age, y | 40.88 ± 9.51 | 40.67 ± 10.79 | 0.97 |
| Fasting glucose, mmol/l | 107.83 ± 38.05 | 104.33 ± 19.32 | 0.80 |
| Fasting insulin, μU/ml | 17.17 ± 9.66 | 18.29 ± 9.14 | 0.80 |
| HOMA-IR, AU | 4.86 ± 3.55 | 4.94 ± 3.12 | 0.97 |
| HBA1c, % | 5.58 ± 0.21 | 5.63 ± 0.45 | 0.84 |
| HBA1c, mmol/mol | 37.43 ± 2.30 | 38.00 ± 4.88 | 0.84 |
| Weight, kg | 136.88 ± 29.82 | 145.07 ± 22.80 | 0.42 |
| BMI, kg/m2 | 49.45 ± 9.11 | 52.23 ± 6.99 | 0.36 |
| Waist-hip ratio | 0.96 ± 0.20 | 0.89 ± 0.14 | 0.31 |
| Waist circumference, cm | 134.67 ± 21.57 | 137.29 ± 20.93 | 0.80 |
| Hip circumference, cm | 142.19 ± 21.50 | 154.43 ± 13.76 | 0.13 |
| Diastolic pressure, mmHg | 83 ± 15 | 83 ± 12 | 0.90 |
| Systolic pressure, mmHg | 135 ± 20 | 131 ± 11 | 0.71 |
| LDL, mg/dl | 122.46 ± 34.75 | 138.13 ± 38.11 | 0.29 |
| HDL, mg/dl | 52.42 ± 20.46 | 45.79 ± 13.77 | 0.31 |
| VLDL, mg/dl | 25.83 ± 12.48 | 25.77 ± 10.85 | 0.99 |
| TG, mg/dl | 129.17 ± 62.39 | 128.87 ± 54.23 | 0.99 |
| CHOL, mg/dl | 202.96 ± 43.95 | 212.53 ± 44.03 | 0.60 |
| CRP, mg/l | 10.50 ± 8.33 | 9.66 ± 8.90 | 0.86 |
| Leptin, mg/ml | 78.36 ± 35.73 | 78.29 ± 36.50 | 1.00 |
| Adiponectin, ng/ml | 7.48 ± 3.75 | 7.95 ± 4.61 | 0.84 |
| GOT, U/l | 26.75 ± 17.65 | 19.33 ± 7.04 | 0.16 |
| GPT, U/l | 44.83 ± 28.35 | 44.07 ± 13.62 | 0.95 |
| GGT, U/l | 32.55 ± 17.78 | 29.73 ± 17.96 | 0.74 |
| Uric acid, mmol/l | 5.45 ± 1.00 | 5.59 ± 1.66 | 0.84 |
| Creatinine, mmol/l | 0.80 ± 0.17 | 0.78 ± 0.11 | 0.75 |
| Urea, mg/dl | 31.29 ± 9.60 | 31.53 ± 10.43 | 0.97 |
| Medication use n (%) | |||
| Lipid-lowering drugs | 1 (4.16) | 0 (0%) | 1.00 |
| Antihypertensive drugs | 7 (29.16) | 2 (13.33) | 0.27 |
| Antiinflamatory drugs | 3 (12.50) | 2 (13.33) | 1.00 |
aValues are shown as Mean ± SD otherwise it is indicate. P values were determined by independent t-test after log-transformated variables
* P values were determined by fisher’s exact test
Abbreviations: AU, arbitrary units; BMI, body mass index; CHOL, total cholesterol; CRP, c-reactive protein; GGT, gamma glutamyl transferase; GOT, aspartate transaminase; GPT, alanine transaminase; HbA1c, glycated haemoglobin A1c; HDL, high-density lipoproteins; HOMA-IR, insulin resitance calculated by homeostatic model assessment; LDL, low-density lipoproteins; RYGP, roux-en-Y gastric bypass; SG, sleeve gastrectomy; TG, triglycerides; VLDL, very low-density lipoprotein.