Table 3. Hazard ratios and 95% confidence intervals of multivariate models for the risk of incident T2D in patients with prediabetes at 3 years of follow-up according to FLI categories.
| Fatty Liver Index | |||
|---|---|---|---|
| <30 | 30–59 | ≥60 | |
| Incident T2D; unadjusted | 1.00 | 2.22 (0.97–5.11) | 4.52 (2.10–9.72) |
| Base model: Incident T2D adjusted for age, sex and educational level | 1.00 | 2.40 (1.03–5.55) | 4.97 (2.28–10.80) |
| Base model adjusted for family history of T2D | 1.00 | 2.31 (1.00–5.36) | 4.82 (2.22–10.48) |
| Base model adjusted for lifestyle* | 1.00 | 2.26 (0.97–5.24) | 4.63 (2.12–10.10) |
| Base model adjusted for hypertension | 1.00 | 2.30 (0.99–5.34) | 4.59 (2.10–10.03) |
| Base model adjusted for lipids (total and HDL cholesterol) | 1.00 | 2.35 (1.01–5.44) | 4.58 (2.09–10.01) |
| Base model adjusted for transaminases (AST, ALT) | 1.00 | 2.22 (0.96–5.14) | 4.13 (1.88–9.04) |
| Base model adjusted for family history of T2D, lifestyle* hypertension, lipids and transaminases | |||
| All | 1.00 | 1.96 (0.85–4.54) | 3.21 (1.45–7.09) |
| Men | 1.00 | 1.53 (0.43–5.40) | 1.70 (0.50–5.74) |
| Women | 1.00 | 1.73 (0.53–5.59) | 4.95 (1.73–14.29) |
*Includes tobacco consumption, alcohol intake, consumption of fruits and vegetables, breakfast and physical activity
T2D, type 2 diabetes mellitus; ALT, alanine transaminase; AST, aspartate transaminase; HDL, high density lipoprotein