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. 2018 Apr 26;19(5):1294. doi: 10.3390/ijms19051294

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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FoxP3 expression in 4 hepatocellular carcinoma (HCC) samples. FoxP3-positive cells belong principally to the CD4⁺ Treg subset, the presence of which is widely variable in different HCC tissues. The distribution pattern of FoxP3 does not show an apparent preference for any tumour sub-localization, as Tregs are found in parenchymal as well as stromal areas of HCC (upper right and lower right images, respectively). Representative images at 10×. The small images are a 200× of the selected area.