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. 2018 May 22;19(5):1543. doi: 10.3390/ijms19051543

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Diagram of a FYN (FYN proto-oncogene)/STAT3 (Signal transducer and activator of transcription 3) signaling for FZD2 in diverse solid tumors and a CaMKII (Ca²⁺/calmodulin-dependent protein kinase II)–TAK1 (TGFβ-activated kinase 1)–NLK (Nemo-like kinase) signaling for FZD6 in mesenchymal-associated phenotype glioblastoma.