Figure 2.

Schematic representation of collagen biosynthesis steps. The main biosynthesis steps of various collagen types are indicated. Green arrows highlight the contiguous processing steps whereas red arrows indicate the final step of collagen assembly into the different structural conformations. Coloured boxes on the right indicate potential alterations occurring during collagen processing at different steps, thus causing abnormalities in the structure and/or assembly. Abbreviations: NC, non-collagenous domain.