Table 5.
Comparison of new GB/GSC marker candidates with established GSC marker candidates
| Test | Points | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| New Candidates | Established Candidates | Control | |||||||||||||
| CD 276 | FREM2 | SPRY1 | SLC47A1 | CD133 | CXCR4 | MELK | PTCH1 | CD9 | CD44 | CYC1 | HPRT1 | H3F3A | RPLP0 | EMC7 | |
| 1 | 4 | 4 | 4 | 3 | 3 | 4 | 4 | 3 | 3 | 4 | 0 | 0 | 4 | 4 | 0 |
| 2 | 4 | 4 | 4 | 4 | 3 | 4 | 4 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 0 |
| 3 | 4 | 4 | 3 | 4 | 3 | 4 | 4 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 0 |
| 4 | 4 | 4 | 4 | 4 | 0 | 0 | 4 | 3 | 0 | 3 | 0 | 4 | 0 | 0 | 0 |
| 5 | 4 | 4 | 4 | 4 | 3 | 4 | 0 | 3 | 3 | 0 | 0 | 0 | 3 | 0 | 0 |
| 6 | 4 | 3 | 4 | 4 | 0 | 0 | 3 | 3 | 0 | 1 | 0 | 3 | 0 | 0 | 3 |
| 7 | 4 | 4 | 4 | 4 | 3 | 4 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3 | 0 |
| 8 | 4 | 4 | 4 | 4 | / | 4 | 4 | 0 | / | 4 | / | / | 0 | 0 | 0 |
| APPT | 4.000 | 3.875 | 3.875 | 3.875 | 2.143 | 3.000 | 2.875 | 1.875 | 2.143 | 2.500 | 0.000 | 1.000 | 0.875 | 0.875 | 0.375 |
APPT = average points per test (rounded to three decimals); 4 points: FDR-corrected p < 0.001 and lfc > 1 (highly significant and highly overexpressed); 3 points: FDR-corrected p < 0.05 and lfc > 0, while criteria for 4 points are not met (significant and overexpressed); 1 point: p < 0.05 and lfc > 0 (overexpressed but borderline non-significant after application of FDR correction); 0 points: either p > 0.05 or lfc < 0 (non-significant or not overexpressed); /: gene not featured on the platform or in the results table.