Table 1.

Differentially expressed long non-coding RNAs (lncRNAs) between sarcomatoid versus epithelioid samples as identified by Bueno et al. [27], and discussed in this article.

Name	log2 Fold Change	Unadjusted p-Value	Comments
PCAT1	−1.227580845	0.000168412
HOTAIR	4.342211972	1.09 × 10−10	Associates with chromatin remodelling complexes to regulate EMT [21]
MALAT1	−0.902533139	2.72 × 10−7
NEAT1	−0.534058107	0.012990525	Identified as an lncRNA with altered (−2.8 fold) expression in MPM [26]
GAS5	0.053707959	0.785538121	GAS5 shown to have altered expression in MPM
HULC	−0.724711448	0.03946186	Known roles in EMT in other cancers [28,29,30]
H19	2.155715056	1.09 × 10−9	Promotes EMT in NSCLC [31], and various other cancers [21]
ZFAS1	−0.443662478	0.018761094	Known regulator of EMT in other cancer settings [32,33,34,35,36]
PVT1	−0.64835701	7.75 × 10−5	Previously identified as an lncRNA with altered expression in MPM [24]
CASC2	−1.434979397	5.64 × 10−12	Overexpression shown to inhibit EMT in lung adenocarcinoma [37]. Associated with Epithelioid and Biphasic samples and high expression associated with better OS in The Cancer Genome Atlas (TCGA) dataset