Figure 1.
Deletion of Panx1 in the cochlea of Gen-Panx1 knockout (KO) mice. (a): Double immunofluorescent staining for Panx1 (green) and Cx30 (red) in the wild-type (WT) mouse cochlea. (b–d): Panx1 expression and deletion in the cochlea of Gen-Panx1 KO mice. White asterisks in panel (b) indicate the absence of Panx1 labeling at the spiral ligament (SPL) in the lateral wall of the Gen-Panx1 KO mice. OC: organ of Corti; OSC: outer sulcus cell; SLM: spiral limbus. Scale bars: (a,b): 50 µm, (c,d): 25 µm.