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(A) Schematic representation of experimental approach on each of the study groups. (B) Implantation of osmotic pumps. Osmotic pumps were implanted subcutaneously in C56BL6 mice after 12 weeks of high fat diet for continuous subcutaneous infusion of placebo, growth hormone (GH) or insulin growth factor type 1 (IGF-1) respectively. HFD: High fat diet.
