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. 2018 May 22;19(5):1537. doi: 10.3390/ijms19051537

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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A proposed mechanism of alcohol-induced dysregulation of GSH. ↓ (red down arrow) and ↑ (red up arrow) indicates decreased and increased, respectively. H₂O—Water, α-kb—Alpha-ketobutyrate, NH₄⁺—Ammonium ion, (green curved arrow) denotes the yielding reaction, ↓ (black down arrow) represents the downstream event(s) and ⊥ indicates inhibition/blockade.

Inline graphic — A proposed mechanism of alcohol-induced dysregulation of GSH. ↓ (red down arrow) and ↑ (red up arrow) indicates decreased and increased, respectively. H₂O—Water, α-kb—Alpha-ketobutyrate, NH₄⁺—Ammonium ion, (green curved arrow) denotes the yielding reaction, ↓ (black down arrow) represents the downstream event(s) and ⊥ indicates inhibition/blockade.