Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagrammatic representation of the developmental changes in AChR composition in humans and mice. Differences between human and mouse expression of ε- and γ-AChR are highlighted and consequences for AChR-deficiency CMS patients and mouse models of AChR-deficiency are compared. Mouse model expressing human γ-AChR in ε-AChR knockout background provides robust model of human CMS phenotype.
