Fig 2. IL-17A production relies on IL-23, IL-6 and IL-1 in a partially redundant manner.

IL-17A⁺ cellular subsets in the tongue of infected WT and Il23a^-/- animals (A-B) or infected Il1ra^-/- mice that were treated with anti-IL-6 antibody and WT controls (C-D). (A, C) Representative plots. Pre-gating is on CD45⁺CD90⁺ cells. Numbers indicate the % of parent in each gate. (B, D) Summary graphs with the total CD90⁺ and CD90⁺IL-17A⁺ cells as well as the respective TCRβ⁺, TCRγδ⁺ and TCR^- subsets according to the analysis shown in A and C. Each symbol represents one animal, the mean of each group is indicated. Graphs show pooled data from three (D) or four (C) independent experiments. (**p<0.01; ***p<0.001). See also S3 Fig.