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. 2018 May 21;14(5):e1007406. doi: 10.1371/journal.pgen.1007406

Table 1. Summary of mRNA stability and changes upon the upshift.

Shown here are the median rates or changes in rates for the specified sets. Destabilized transcripts were identified using the criteria of a significant (FDR < 0.01) change in estimated degradation rates and at least a doubling of the rate of clearance.

Pre-shift Post-shift Change in specific rate (min−1) Fold-change specific rate
specific rate (min−1) half-life (min) specific rate (min−1) half-life (min)
All transcripts 0.100 6.92 0.110 6.32 0.00865 1.08
Destabilized (n = 78) 0.0732 9.46 0.229 3.02 0.158 3.06
No difference detected (n = 4781) 0.101 6.89 0.108 6.40 0.00728 1.07