Table 1.
Clinical characteristics of older patients diagnosed with regional gastric cancer by no treatment and treatment
| Characteristic, n (%) | Total 5972 |
No treatment 1586 (26.56) |
Treatment 4386 (73.44) |
p |
|---|---|---|---|---|
| Year | < 0.001 | |||
| 2001–2003 | 2197 (36.79) | 710 (44.77) | 1487 (33.90) | |
| 2004–2006 | 1955 (32.74) | 525 (33.10) | 1430 (32.60) | |
| 2007–2009 | 1820 (30.48) | 351 (22.13) | 1469 (33.49) | |
| SEER region | < 0.001 | |||
| Northeast | 1241 (20.78) | 205 (12.93) | 1036 (23.62) | |
| Midwest | 527 (8.82) | 91 (5.74) | 436 (9.94) | |
| South | 1102 (18.45) | 232 (14.63) | 870 (19.84) | |
| West | 3102 (51.94) | 1058 (66.71) | 2044 (46.60) | |
| Age (years) | < 0.001 | |||
| 65–69 | 743 (12.44) | 166 (10.47) | 577 (13.16) | |
| 70–74 | 1358 (22.74) | 344 (21.69) | 1014 (23.12) | |
| 75–79 | 1424 (23.84) | 351 (22.13) | 1073 (24.46) | |
| ≥ 80 | 2447 (40.97) | 725 (45.71) | 1722 (39.26) | |
| Sex | 0.005 | |||
| Female | 2621 (43.89) | 648 (40.86) | 1973 (44.98) | |
| Male | 3351 (56.11) | 938 (59.14) | 2413 (55.02) | |
| Race | 0.001 | |||
| White | 3678 (61.59) | 944 (59.52) | 2734 (62.33) | |
| Black | 935 (15.66) | 260 (16.39) | 675 (15.39) | |
| Asian | 651 (10.90) | 153 (9.65) | 498 (11.35) | |
| Othera | 1359 (22.76) | 382 (24.09) | 977 (22.28) | |
| Marital statusb | 0.537 | |||
| Single (never married) | 459 (7.95) | 112 (7.33) | 347 (8.17) | |
| Married | 3281 (56.79) | 870 (56.90) | 2411 (56.76) | |
| Divorced | 356 (6.16) | 88 (5.76) | 268 (6.31) | |
| Widowed | 1681 (29.10) | 459 (30.02) | 1222 (28.77) | |
| Median household incomec | 0.059 | |||
| Q1 | 1463 (24.50) | 368 (23.20) | 1095 (24.97) | |
| Q2 | 1469 (24.60) | 416 (26.23) | 1053 (24.01) | |
| Q3 | 1531 (25.94) | 427 (26.92) | 1104 (25.17) | |
| Q4 | 1509 (25.27) | 375 (23.64) | 1134 (25.85) | |
| At least 12 years of educationc | 0.054 | |||
| Q1 | 1424 (24.84) | 388 (24.49) | 1036 (24.61) | |
| Q2 | 1427 (24.90) | 371 (24.38) | 1056 (24.08) | |
| Q3 | 1448 (25.26) | 415 (27.27) | 1033 (24.54) | |
| Q4 | 1433 (25.00) | 348 (22.86) | 1085 (25.77) | |
| Charlson comorbidity index | < 0.001 | |||
| 0 | 3359 (56.25) | 1252 (78.94) | 2107 (48.04) | |
| 1 | 1339 (22.42) | 166 (10.47) | 1173 (26.74) | |
| ≥ 2 | 1274 (21.33) | 168 (10.59) | 1106 (25.22) | |
| Histology | < 0.001 | |||
| Adenocarcinoma | 5605 (93.85) | 1437 (90.91) | 4168 (95.03) | |
| Squamous cell carcinoma | 121 (2.03) | 70 (4.41) | 51 (1.16) | |
| Other | 246 (4.12) | 79 (4.98) | 167 (3.81) | |
| Tumor location | 0.001 | |||
| Pylorus antrum/pylorus | 2295 (38.43) | 579 (36.51) | 1716 (39.12) | |
| Gastric, NOS | 901 (15.09) | 286 (18.03) | 615 (14.02) | |
| Body/less or greater | 1859 (31.13) | 466 (29.38) | 1393 (31.76) | |
| Overlapping | 653 (10.93) | 190 (11.98) | 463 (10.56) | |
| Fundus | 264 (4.42) | 65 (4.10) | 199 (4.54) | |
| Differentiation | < 0.001 | |||
| Well/moderate | 1497 (25.07) | 357 (22.51) | 1140 (25.99) | |
| Poor/undifferentiated | 3985 (66.73) | 1023 (64.50) | 2962 (67.53) | |
| Unknown | 490 (8.20) | 206 (12.99) | 284 (6.48) | |
| Distance to nearest NCI (mi) | 0.001 | |||
| < 25 | 3456 (58.07) | 977 (61.46) | 2485 (56.85) | |
| 25–49.9 | 887 (14.91) | 239 (15.13) | 648 (14.82) | |
| ≥ 50 | 1608 (27.02) | 370 (23.42) | 1238 (28.32) |
IQR interquartile range, NCI National Cancer Institute, SEER Surveillance, Epidemiology, and End Results
a
Hispanic and Native American
b
Unknown: 545 patients
c
Defined using Census zip code data and categorized into quartiles